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Different from traditional medical devices, customized prostheses made with 3D printing realizes a transition from one size fits all to tailor-made precision. The book systematically introduces the basic issues, design preparation, clinical applications, potential risks, precautions, and regulatory supervision of 3D printing personalized prostheses in the field of orthopedics. It will be a theoretical and technical reference for clinical doctors, engineering technicians, regulatory and research personnel engaged in the application of 3D printing personalized prostheses.