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Bioinformatics entails the creation and advancement of databases, algorithms, computational and statistical techniques and theory to solve problems arising from the analysis of biological data. This book is an introductory text that links issues in biology to computer science to offer a clear picture of the principles driving bioinformatics. Database concepts and biological database management systems and designing a biological database have been clearly elucidated. Detailed information on sequence analysis has also been provided. The applications of bioinformatics also have been explained from a genomics and proteomics perspective.