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This book constitutes the thoroughly refereed post-proceedings of the First International Workshop on Knowledge Discovery and Emergent Complexity in Bioinformatics, KDECB 2006, held in Ghent, Belgium, in May 2006, in connection with the 15th Belgium-Netherlands Conference on Machine Learning.§The 12 revised full papers presented, including 4 invited talks, were carefully reviewed and selected for inclusion in the book. The papers cover various topics in the areas of knowledge discovery and emergent complexity research in bioinformatics, thus giving a representative overview of the current state of affairs in this field. Topics of interest for the workshop included sequence assembly, clustering, mapping and alignment, modeling molecular interactions, genetic regulatory and protein interaction networks, biological information networks, dynamical systems approach, network dynamics, protein identification, pathway extraction, bayesian networks, protein folding, and biological data mining.
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