Contact
Hoe winkelen bij ons werkt
Bezorging
Winkelgids
Engels
249 b
Tot 30 dagen retourrecht
Klanten kochten ook
/
Gebonden (paperback)
16.17
€
/
Gebonden (paperback)
25.82
€
/
Kalender
53.87
€
/
Gebonden (paperback)
10.24
€
/
Gebonden (paperback)
36.07
€
/
Gebonden (paperback)
13.26
€
/
Gebonden (paperback)
10.95
€
/
Gebonden (paperback)
8.23
€
The excision-repair of ultraviolet-induced lesions in DNA involves a recogni tion and incision step which is followed by excision of the damaged material, DNA repair resynthesis, and sealing of the fmal gap by polynucleotide ligase (e.g. Howard-Flanders, 1968). The initial incision step appears to require an endo nuclease which is absent in the uvrA and uvrR mutants of E. eoli K12 (Braun et al., Part A of this book). The polAl strains are deficient in DNA polymerase I activity (de Lucia and Cairns, 1969) and are partially deficient in repairing single-strand breaks in DNA (incision breaks) produced by the excision-repair process (Kanner and Hanawalt, 1970; Paterson et al., 1971). Most of the repair of incision breaks which occurs in the polAl strain appears to require DNA polymerase III (Youngs and Smith, 1973b). Thus, both DNA polymerases I and III have been implicated in the DNA repair resynthesis step of the excision-repair process. Masker et al. (1973) have shown that DNA polymer ase 11 (deficient in polB mutants, Campbell et al., 1972) is involved in UV-induced repair replication in toluene-treated cells which lack both DNA polymerase I and normal DNA replication. However, DNA polymerase 11 is probably not involved in a major way in repair processes in vivo, since wild-type or polAl cells which also contain a polR mutation are no more sensitive to UV or X-radiation than the related polB+ strains (Campbell et al., 1972; Youngs and Smith, 1973e).
Informatie over het boek
Engels
Geef dit boek vandaag nog cadeau
Dat gaat heel eenvoudig
1 Voeg het boek toe aan je winkelwagentje en selecteer Als cadeau bezorgen 2 Je krijgt van ons per omgaand een voucher 3 Het boek wordt bezorgd op het adres van de ontvangerDit vind je misschien ook interessant
/
Gebonden (paperback)
14.77
€
/
Gebonden (paperback)
10.95
€
/
Gebonden (paperback)
11.15
€
Hoi! Ik ben Libroamiko, je boekadviseur.
Hoe kan ik je helpen?