The Biology of Antimicrobial Resistance

The Biology of Antimicrobial Resistance: From Host Defense to Novel Therapeutic Frontiers Antimicrobial resistance is one of the most complex and rapidly evolving challenges in modern medicine, threatening the effectiveness of therapies against bacterial infections worldwide. Understanding antimicrobial resistance requires more than identifying resistant organisms-it demands an integrated view of microbial survival, host defense, pathogen-host interactions, and emerging therapeutic strategies. The Biology of Antimicrobial Resistance: From Host Defense to Novel Therapeutic Frontiers explores the biological foundations and contemporary dimensions of antimicrobial resistance, connecting molecular resistance mechanisms with bacterial adaptation, host defense, infection biology, and innovative approaches to therapy. Designed for students, researchers, microbiologists, biomedical scientists, and healthcare professionals, this book provides a multidisciplinary perspective on how pathogens evade antimicrobial treatment and how scientific advances may contribute to overcoming resistance. By bringing together microbial mechanisms, host responses, molecular insights, and emerging therapeutic concepts, the book highlights the importance of understanding infection as a dynamic interaction between pathogen and host. This work aims to provide a useful scientific resource for readers seeking to understand not only how antimicrobial resistance develops, but also how research into host defense and pathogen biology can inform the development of new therapeutic strategies.